glucosamine supplement, GLUCOSAMINE CHONDROITIN & MSM, reduce joint stiffness 2B
One study found that combining MSM with glucosamine and chondroitin was more effective at decreasing pain and stiffness in people with knee osteoarthritis than glucosamine and chondroitin alone. It's believed that MSM inhibits NF-kB, a protein complex involved in inflammatory responses in your body.