Core Nutritionals - Bolic- 120 Capsules - OG Black FormulaTestosterone Booster & PCT!!orCore Nutritionals - Bolic- 120 Capsules - New Platinum FormulaTestosterone Booster & PCT!! Core Hard, Core Alpha, Core Sear, Core Poise & Many More!!! Buy More, Save More!! WHAT IS IT?Core Nutritionals BOLIC is a Performance Enhancing and Muscle Building SupplementWHAT DOES IT DO?Core Nutritionals BOLIC is a Laxogenin & PeakO2™ based supplement. Laxogenin, also known as 5-Alpha Hydroxy Laxogenin, is a naturally occurring plant-based steroidal sapogenin found in the Smilax Sieboldii plant. Laxogenin has been shown to yield anabolic effects that favor building muscle such as increased protein synthesis/production.PeakO2™ is an organic-certified combination of six Ayurvedic mushroom strains. These mushrooms are powerful adaptogens, which allow athletes to “adapt” to and overcome physical and mental stress, giving you the extra edge you want to take your training to the next level. PeakO2™ is brought to us by the ingredient masterminds over at Compound Solutions. PeakO2™ has been shown to boost both endurance AND power, it’s a real powerhouse ingredient. Combined with a sensible dieting and training regime, Core Nutritionals BOLIC will help you build muscle at a faster rate.WHEN DO I TAKE IT?Core Nutritionals BOLIC should be taken at a consistent time of day every day. Whether it be first thing in the morning or before training, whichever time works for you to be able to consume Core Nutritionals BOLIC daily.Simply consume 2 capsules, two times per day, with at least 250ml of water.HOW LONG DOES IT TAKE TO WORK?You will notice the initial effects of Core Nutritionals BOLIC within the 1-2 weeks of use. You will experience increased muscle recovery, increased strength and increased training intensity. You may also notice increased muscle fullness, increased vascularity and increased libido.Combined with a sensible dieting and training regime tailored to your health and fitness goals, the increased natural testosterone levels created by Core Nutritionals BOLIC will start to make substantial changes to your physique within the first 4 weeks of use. You will continue to experience physique changing results indefinitely, provided you stick to your dieting and training regime. Nutrition Facts: Serving Size: 2 Vegetable Capsules Servings Per Container: 60Amount Per Serving% Daily Value*5-Alpha Hydroxy Laxogenin 100 mg-Peak02 1000 mg-Peak02([Cordyceps Militaris (Cordyceps) (Root), Ganoderma Lucidim (Reishi) (Root), Pleurotus eryngii (King Trumpet)(Root)Lentinula Edodes (Shiitake)(Root), Hericium Erinaceus (Lions Mane) (Root), And Trametes Versicolor (Turkey Tail) (Root))Ingredients: Rice Flour, Cellulose (Veggie Capsule), Magnesium Stearate, Silicon Dioxide.. About this Item: Natural athletes are often left with an impossible choice: accept that highly anabolic compounds come along with a host of negative side effects, disqualify them competition, and render them an “enhanced athlete,” or turn to these same compounds to reap their benefits on muscle anabolism and protein synthesis. A long line of supplements has purported to reconcile this problem, promising increases to muscle protein synthesis and nitrogen synthesis comparable to AAS (anabolic androgenic steroids). Such promises, of course, were empty, as the real-world effects of these compounds never matched the laboratory results.Laxogenin appears to be different. While no natural compound will deliver the same effects as PEDs (performance enhancing drugs), and it’s irresponsible to suggest otherwise, Laxogenin does, in fact, seem to operate through the same mechanism of action that makes these compounds so effective – the so-called PI3K/Akt signaling pathway. This pathway directly regulates a process known as “protein turnover,” the ratio between protein synthesis (where your body “builds” muscle tissue) and protein degradation (where your body “destroys” muscle tissue to feed other physiologic processes). In situations where protein synthesis exceeds degradation, your body is in a state of ‘net positive protein turnover,’ commonly known as “anabolism.” While the data is still emerging, Laxogenin appears to induce this very state by significantly enhancing protein synthesis through the very same PI3K/Akt pathway. These trials show Laxogenin simultaneously reducing protein degradation, perhaps inducing muscle into a state of net positive protein turnover.Combined with the patented ingredient Peak O2, clinically demonstrated to increase power output, endurance, and other metrics of exercise performance, BOLIC is a fully natural but fully effective performance supplement. It not only increases exercise performance, but makes the underlying response to exercise more efficient – ensuring that your hardwork is paying off! -----------------------------------------------------------------The Science Laxogenin:Laxogenin, also known as 5a-hydroxy laxogenin is plant-based steroid derived Smilax sieboldii. Laxogenin is part of the Brassinosteroid class of plant hormones, polyhydroxylated derivatives 5a-cholestane – and thus is structurally to the cholesterol-backbone steroid hormones found in animals and ecdysteroids found in insects. Brassinosteroids function in plant tissue as steroid hormones function in animal tissue, namely by stimulating protein synthesis and inhibiting protein degradation via the PI3K/Akt signaling cascade. Unlike steroid hormones, however, both Brassinosteroids generally, and 5a¬¬-hydroxy laxogenin specifically, show no binding affinity to the androgen receptor (AR) in vitro.While evidence is still emerging, the extant animal data on Laxogenin is promising. In a trial in healthy rats fed a protein-controlled diet (39.4% protein content), oral administration of Laxogenin “increased food intake, body weight gain…[and]…lean body mass.” Upon dissecting the animals, researchers demonstrated that both phenotypic variation and muscle hypertrophy occurred. Laxogenin “significantly increased” Type IIa and IIx muscle fibre phenotype and increased Type I and Type IIa cross-section. As noted above, Laxogenin dose- and time-dependently increased Akt phosphorylation in rat muscle cells at levels similar (though less) than insulin and IGF-1 controls. Protein synthesis as a result PI3K/Akt activation increased by approximately 35%, while protein degradation decreased by approximately 9% - suggesting that administration of Laxogenin promotes net positive protein conservation in animal muscle.PeakO2™:PeakO2™ is an organic-certified combination of six Ayurvedic mushroom strains extracted for their principal bioactives (Cordyceps militaris (Cordyceps), Ganoderma lucidim (Reishi), Pleurotus eryngii (King Trumpet), Lentinula edodes (Shiitake),Hericium erinaceus (Lions Mane), and Trametes versicolor (Turkey Tail). The results of several human clinical trials on this compound suggest that it may meaningfully and dose-dependently impact several key metrics in exercise performance and physiology. A recent trial on 13 healthy, exercising adults consuming either 1.3 grams of PeakO2 or placebo, for example, demonstrated significant increases to oxygen kinetics, aerobic power and time to fatigue. In the adults receiving the 1.3g of PeakO2 for three weeks, VO2max (a measure of aerobic capacity) increased by 11% as compared to 1.8% in placebo; TTE (total time to exhaustion) increased by 8.2%; and peak power increased by 10%.The results were similar in an additional study with 40 healthy adults, provided both low and high-dose PeakO2 for 28 days and compared with placebo. In this trial, participants receiving the mushroom extract experienced statistically significant increases to both VO2max and heart-rate economy – suggesting that PeakO2’s effects are both systemic and cumulative. That is, not only does PeakO2 exert its effects on the entirety of the human cardiovascular system – likely due to the multiple mechanisms of action in the mushroom blend – but these effects accumulate over time.These results suggest that PeakO2 may have beneficial effects on:Workout durationTime to exhaustionMaximum power outputPeak strengthAnaerobic peak powerOxygen utilization during exerciseAbility to uptake oxygenExercise capacity **BY PLACING AN ORDER YOU AGREE TO THE FOLLOWING** Shipping is free for the continental U.S. only! This means we will ship to the lower 48 states for free. If you live outside the continental U.S. you will be charged shipping. Any taxes or duties for orders outside the U.S. are the responsibility of the customer to pay. All orders are shipped within 24 hours excluding weekends and holidays. Orders received before 11am Eastern time will be shipped out the same day. Weekends and holidays excluded. We are a business selling on eBay. Our normal hours of operation are Monday-Friday 9am-5pm Eastern time. We ship orders and answer messages during these times only. Messages are answered twice daily so please be patient. We will answer all questions! Shipping is free! All orders under 13 ounces will be shipped via USPS First Class Mail. All orders 14 ounces and over will be shipped using one of the following- USPS Parcel Select, USPS Priority Mail, UPS Ground or UPS Sure Post. We ship from Florida. Shipping times vary depending on locations. We do offer a 2-day expedited shipping service. If you need your package by a certain date, we suggest using an expedited service. There is no delivery guarantees with the standard free shipping.All US orders are shipped via USPS First Class, USPS Priority Mail, UPS Ground, UPS Sure Post, UPS 3 Day Select or UPS 2 Day Air. Orders shipped using USPS can be tracked on their website. Orders shipped using UPS can be tracked at their website. Orders are typically shipped within 24 hours, excluding weekends and holidays. Priority Mail Packages typically arrive in 2-4 business days. USPS First Class, UPS Sure Post and UPS Ground packages typically arrive in 5-8 business days. Online tracking is available for all packages except APO/Military. For APO/Military packages, you may request a copy of the shipping label to confirm the shipment date and mailing address. The vast majority of APO/Military orders arrive within 15-30 days, depending on the class of service chosen.Please allow 48 hours after your package has shipped before seeing movement through the USPS or UPS system. Once your package has shipped, you will be emailed a shipping confirmation. This email will provide your tracking number. While issues with shipments are rare, sometimes the packages may be delayed or damaged upon arrival. If the package arrives damaged, we will replace your product free of charge. In order to do so, we must receive a picture of the damaged product within 72 hours of receiving the package. Claims sent after this time frame will be denied. This information will be verified via the package tracking number. Packages scanned delivered at the address on the package will not be refunded or reshipped due to the package being lost or missing. Any merchandise received damaged must be reported to Us within 24 hours of receipt. We will work with you to fix the inconvenience. We will contact the shipper for inspection of the box and contents. Do not dispose of an packing materials as they will be inspected by the shipper. Please take pictures immediately of the damaged item. *The products and the claims made about specific products on or through this site have not been evaluated by Coastal Distributions or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Under US FDA law, it is illegal for a manufacturer to make any medical claims for health supplements. All statements made are intended for informational purposes only. These statements have not been evaluated or approved by the FDA, and our products are not intended to diagnose, treat, cure or prevent any disease.
